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Product Details:
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| Product Name: | Eptifibatide 98% Powder | Active Ingredient: | Eptifibatide |
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| Packing: | 25kg/Drum | Specification: | 10mg & 1g |
| Function: | Research | Appearance: | White Powder |
| Sample: | Available | Test Method: | HPLC |
| Highlight: | 1g/Bottle Growth Hormone,98% Eptifibatide Powder,Eptifibatide High Growth Hormone |
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Eptifibatide 98% Powder Cas 188627-80-7 10mg/Bottle 1g/Bottle 10 Bottles/Box
What is Eptifibatide?
Eptifibatide is a kind of synthetic cyclic hexapeptide consisting of 6 amino acids and 1 mercaptopropionyl residue. It is capable of binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibiting the platelet aggregation, thus blocking the binding of the fibrinogen, von Willebrand factor and other adhesive ligands. It is indicated for the treatment of acute coronary syndrome (ACS) and Percutaneous coronary intervention (PCI). It is able to reduce the risk of acute cardiac ischemic events in patients with unstable angina or non-ST segment-elevation myocardial infection. It is often used in combination with aspirin or clopidogrel and heparin. It can be manufactured through solution-phase peptide synthesis, and can be purified by preparative reverse-phase liquid chromatography and lyophilization.
| Product Name: | Eptifibatide |
| Synonyms: | Eptifibatide acetate salt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2, >99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDE BRIDGE, MPA1-CYS6);Intrifiban |
| CAS: | 188627-80-7 |
| MF: | C35H49N11O9S2 |
| MW: | 831.96 |
| EINECS: | 641-366-7 |
| Product Categories: | Intermediates & Fine Chemicals;Peptides;Pharmaceuticals;GMP |
| Mol File: | 188627-80-7.mol |
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Function
| Eptifibatide is a cyclic heptapeptide composed of six amino acids and one mercaptopropionyl residue. The cyclization is completed via a disulfide linkage between the cysteine and the mercaptopropionyl moieties. The lysine-glycine-aspartate component of eptifibatide is highly specific for the GPIIb/IIIa receptor, with low binding affinity, as indicated by the rapid dissociation constant. Because of this, eptifibatide is a reversible, parenterally administered antagonist of platelet aggregation. |
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